The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2006
Filed:
Oct. 28, 2002
Craig J. Gerard, Dover, MA (US);
Norma P. Gerard, Dover, MA (US);
Charles R. Mackay, Watertown, MA (US);
Paul D. Ponath, Boston, MA (US);
Theodore W. Post, Newton, MA (US);
Shixin Qin, Lexington, MA (US);
Craig J. Gerard, Dover, MA (US);
Norma P. Gerard, Dover, MA (US);
Charles R. Mackay, Watertown, MA (US);
Paul D. Ponath, Boston, MA (US);
Theodore W. Post, Newton, MA (US);
Shixin Qin, Lexington, MA (US);
Children's Medical Center Corporation, Boston, MA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Brigham & Women's Hospital, Boston, MA (US);
Abstract
The present invention relates to a method of identifying an inhibitor of a mammalian (e.g., human) C—C chemokine receptor 3 (CCR3), comprising combining (a) a compound to be tested, (b) a host cell expressing a recombinant protein comprising a mammalian CCR3, and (c) a ligand of said receptor, under conditions suitable for binding of ligand to said receptor, and detecting or measuring the formation of a receptor-ligand complex. Inhibition of complex formation by the compound is indicative that the compound is an inhibitor.