The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2006

Filed:

Jun. 25, 2001
Applicants:

Hiroaki Oka, Hirakata, JP;

Ryuta Ogawa, Moriguchi, JP;

Tetsuo Yukimasa, Hirakata, JP;

Inventors:

Hiroaki Oka, Hirakata, JP;

Ryuta Ogawa, Moriguchi, JP;

Tetsuo Yukimasa, Hirakata, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/08 (2006.01); A61B 5/00 (2006.01); A61N 1/30 (2006.01); A61M 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method and apparatus for readily and reliably screening olfactory mucosa stimulating compounds are provided. An olfactory mucosa stimulating compound is sprayed through an atomizing nozzleto an olfactory mucosa of a rat fixed in a test animal fixing device. A measuring electrode portionis implanted in an olfactory bulb of the rat for measuring an electrical signal generated in the olfactory bulb. Efficacy of the olfactory mucosa stimulating compound is determined based on a correlation between an electrical signal measured by the measuring electrode portionwhen the olfactory mucosa stimulating compound is sprayed on the olfactory mucosa of the rat and a physiological response induced in the rat.


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