The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6992181 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 31, 2006

Filed:

Aug. 23, 2004
Applicants:

Nigel Eric Tooke, Knivsta, SE;

Philip Landeg Thomas, Cardiff, GB;

Michael Kenneth Kenrick, Caerphilly, GB;

Inventors:

Nigel Eric Tooke, Knivsta, SE;

Philip Landeg Thomas, Cardiff, GB;

Michael Kenneth Kenrick, Caerphilly, GB;

Assignee:

Gyros AB, Uppsala, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a method and apparatus for the isolation of DNA or cell nuclei or a mixture thereof from cell samples in a CD device. The method includes treating a suspension of whole cells with a lysis reagent so as to lyse the cytoplasmic membrane and at least some of the nuclear membranes, and introducing the lysate into micro-channels of a microfabricated apparatus in which each of the micro-channels is provided with a barrier disposed in the channel to impede the passage or flow of DNA and cell nuclei while allowing the passage of liquid through the micro-channel so that a mesh comprising DNA is formed in the channel.


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