The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2006

Filed:

Dec. 10, 2004
Applicants:

Raymond A. Hui, Indianapolis, IN (US);

Gerald F. Sigler, Carmel, IN (US);

Richard T. Root, Fishers, IN (US);

Wei Yuan, Fishers, IN (US);

Inventors:

Raymond A. Hui, Indianapolis, IN (US);

Gerald F. Sigler, Carmel, IN (US);

Richard T. Root, Fishers, IN (US);

Wei Yuan, Fishers, IN (US);

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); C07K 17/02 (2006.01); C12N 5/12 (2006.01); G01N 33/531 (2006.01); C07D 217/26 (2006.01);
U.S. Cl.
CPC ...
Abstract

Analogs of saquinavir functionalized at the quinoline portion of the molecule are described. These include pyridyl analogs (replacing the quinoline ring) with a functional handle out of the ring allowing for elaboration with linkers terminated by a functional group such as an activated ester which are useful for attaching the molecule to other entities such as proteins, polysaccharides, and the like. Analogs of saquinavir derivatized out of the quinoline ring are also described.


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