The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6992101 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 31, 2006

Filed:

Nov. 06, 2003
Applicants:

Donald L. Bussolotti, Ledyard, CT (US);

Ronald B. Gammill, Schoolcraft, MI (US);

Jana Polivkova, Ledyard, CT (US);

Inventors:

Donald L. Bussolotti, Ledyard, CT (US);

Ronald B. Gammill, Schoolcraft, MI (US);

Jana Polivkova, Ledyard, CT (US);

Assignee:

Pfizer, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/04 (2006.01); C07D 495/02 (2006.01); A61K 31/407 (2006.01); A61K 31/381 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of formula (I)the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R', R″, R′″, and Z are as defined herein; pharmaceutical compositions thereof; and uses thereof in treating diabetes, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis, and tissue ischemia.


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