The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2006

Filed:

Jul. 13, 2004
Applicants:

Heike Radeke, Dedham, MA (US);

Paul E. Persons, Westborough, MA (US);

James R. Hauske, Concord, MA (US);

Inventors:

Heike Radeke, Dedham, MA (US);

Paul E. Persons, Westborough, MA (US);

James R. Hauske, Concord, MA (US);

Assignee:

Sepracor Inc., Marlborough, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 221/00 (2006.01); C07D 223/00 (2006.01); A61K 31/438 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

One aspect of the present invention relates to spirocyclic compounds. Another aspect of the present invention relates to the use of the spirocyclic compounds as ligands for mammalian G-protein-coupled receptors or sigma receptors. The present invention also relates to methods of modulating the activity of a G-protein-coupled receptor or a sigma receptor in a mammal using the spirocyclic compounds of the present invention. The present invention also relates to methods of treating various diseases in a mammal using the spirocyclic compounds of the present invention.


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