The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2006
Filed:
Dec. 27, 1999
Masaaki Mori, Ibaraki, JP;
Yukio Shimomura, Ibaraki, JP;
Shiro Takekawa, Ibaraki, JP;
Tsukasa Sugo, Ibaraki, JP;
Yoshihiro Ishibashi, Ibaraki, JP;
Chieko Kitada, Osaka, JP;
Nobuhiro Suzuki, Ibaraki, JP;
Masaaki Mori, Ibaraki, JP;
Yukio Shimomura, Ibaraki, JP;
Shiro Takekawa, Ibaraki, JP;
Tsukasa Sugo, Ibaraki, JP;
Yoshihiro Ishibashi, Ibaraki, JP;
Chieko Kitada, Osaka, JP;
Nobuhiro Suzuki, Ibaraki, JP;
Takeda Chemical Industries, Ltd., Osaka, JP;
Abstract
The present invention provides a method for screening a compound or its salt that alters the binding property between MCH or its salt and SLC-1 or its salt, characterized by using MCH or its derivative or a salt thereof and SLC-1 or its salt is useful for screening an SLC-1 agonist which can be used not only as an appetite (eating) promoting agent but also as a prophylactic/therapeutic agent for weak pains, atonic bleeding, before and after expulsion, subinvolution of uterus, cesarean section, induced abortion, galactostasis, and the like, and an SLC-1 antagonist which can be used not only as an antiobestic agents (drug), an appetite (eating) modulator, and the like, but also as a prophylactic/therapeutic agent for hyperstimulation, ankylosing uterine contractions, fetal distress, uterine rupture, cervical laceration, preterm delivery, Prader-Wili syndrome and the like.