The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2006
Filed:
Jun. 28, 2001
Jinhua an, Palo Alto, CA (US);
Karen S. Leu, Saratoga, CA (US);
Edwin S. Lennox, Standford, CA (US);
John H. Musser, San Carlos, CA (US);
Jinhua An, Palo Alto, CA (US);
Karen S. Leu, Saratoga, CA (US);
Edwin S. Lennox, Standford, CA (US);
John H. Musser, San Carlos, CA (US);
Pharmagenesis, Inc., Palo Alto, CA (US);
Abstract
An acid-modified arabinogalactan protein composition, having an arabinose-galactaose ratio of less than 3.5:1, comprising 5–10% Rha, 20–35% Gal, and less than 5% Glc, prepared from, is useful for treating a number of conditions. For example, an acid-modified arabinogalactan protein composition having features of the invention is useful for stimulating hematopolesis, inducing the proliferation of megakaryocytes, inducing the maturation of megakaryocytes, and stimulating the production of IL-1β, IL-6, TNF-α, IFN-γ, GM-CSF, G-CSF, and neutrophils, and stimulating the action of neutrophils; stimulating the immune and/or hematopoietic system of a mammal suffering from neutropenia, anemia, thrombocytopenia, exposure to cytotoxic agents, exposure to radiation, cachexia, emesis, and drug withdrawal symptoms; and is effective to restore the immune response to infection, in immunosuppressive conditions, and to protect hepatic cells in hepatitis B.