The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2006
Filed:
Aug. 10, 1999
Robert S. Lowe, North Wales, PA (US);
Kathrin U. Jansen, Doylestown, PA (US);
Joseph G. Joyce, Lansdale, PA (US);
William L. Mcclements, Doylestown, PA (US);
James C. Cook, Iii, Lansdale, PA (US);
Jessica Ching-yee Ling, Bensalem, PA (US);
Michael P. Neeper, Collegeville, PA (US);
Robert S. Lowe, North Wales, PA (US);
Kathrin U. Jansen, Doylestown, PA (US);
Joseph G. Joyce, Lansdale, PA (US);
William L. McClements, Doylestown, PA (US);
James C. Cook, III, Lansdale, PA (US);
Jessica Ching-Yee Ling, Bensalem, PA (US);
Michael P. Neeper, Collegeville, PA (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Human Papillomavirus virus like particles (VLPs) have been constructed so that they contain a modified L2 protein. The L2 protein has been minimized and is fused to a second protein or peptide. The fused protein is incorporated into the VLP and the VLP can deliver the protein to a cell. The modified VLPs can be used to increase the breadth of immune response in vaccine preparations or to deliver other proteins of interest.