The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2006

Filed:

Jan. 17, 2003
Applicants:

Solomon S. Steiner, Mount Kisco, NY (US);

Cohava Gelber, Hartsdale, NY (US);

Robert S. Feldstein, Yonkers, NY (US);

Roderike Pohl, Sherman, CT (US);

Inventors:

Solomon S. Steiner, Mount Kisco, NY (US);

Cohava Gelber, Hartsdale, NY (US);

Robert S. Feldstein, Yonkers, NY (US);

Roderike Pohl, Sherman, CT (US);

Assignee:

MannKind Corporation, Valencia, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/12 (2006.01); A61K 9/72 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions containing biologically active molecules encapsulated in self-assembling, diketopiperazine microspheres (TECHNOSPHEREs™) and methods for making and administering such compositions are described herein. The compositions can be used to immunize individuals against agents of biological warfare. The biologically active molecules include atropine, antibodies, antigens, and antibiotics. The compositions can be placed in an inhalation device for self-administration. Pulmonary delivery of TECHNOSPHERE™ encapsulated atropine, antibodies, vaccines, and antibiotics provides an accelerated onset of immunity to the targeted disease. Furthermore, the TECHNOSPHERE™ encapsulated atropine, antibodies, vaccines, and antibiotics are stable formulations, suitable for stockpiling, rapid dissemination and mass treatment.


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