The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2006

Filed:

Apr. 10, 2002
Applicants:

A. Douglas Kinghorn, Chicago, IL (US);

John M. Pezzuto, River Forest, IL (US);

Baoliang Cui, Palisades Park, NJ (US);

Gloria L. Silva, Cordoba, AR;

Min You, Indianapolis, IN (US);

Inventors:

A. Douglas Kinghorn, Chicago, IL (US);

John M. Pezzuto, River Forest, IL (US);

Baoliang Cui, Palisades Park, NJ (US);

Gloria L. Silva, Cordoba, AR;

Min You, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/46 (2006.01); C07D 451/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds and methods of modulating the activity of P-glycoproteins are disclosed. The method utilizes compounds derived fromThe compounds overcome multidrug resistance and can be used therapeutically to enhance performance of therapeutic drugs, like chemotherapeutic drugs and antibiotics.


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