The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2006
Filed:
Jul. 23, 2003
YE Hua, La Jolla, CA (US);
Hiep the Luu, San Diego, CA (US);
Fora P. Chan, San Diego, CA (US);
Theodore O. Johnson, Jr., San Diego, CA (US);
Siegfried Heinz Reich, San Diego, CA (US);
Donald James Skalitzky, San Diego, CA (US);
Yi Yang, San Diego, CA (US);
Thomas F. Hendrickson, Encinitas, CA (US);
Shao Song Chu, Encinitas, CA (US);
Brian Walter Eastman, San Diego, CA (US);
Ye Hua, La Jolla, CA (US);
Hiep The Luu, San Diego, CA (US);
Fora P. Chan, San Diego, CA (US);
Theodore O. Johnson, Jr., San Diego, CA (US);
Siegfried Heinz Reich, San Diego, CA (US);
Donald James Skalitzky, San Diego, CA (US);
Yi Yang, San Diego, CA (US);
Thomas F. Hendrickson, Encinitas, CA (US);
Shao Song Chu, Encinitas, CA (US);
Brian Walter Eastman, San Diego, CA (US);
Agouron Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
Compounds of the formula:where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.