The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2006

Filed:

Nov. 01, 1999
Applicants:

Louis E. Henderson, Mt. Airy, MD (US);

Larry O. Arthur, Walkersville, MD (US);

William G. Rice, Frederick, MD (US);

Inventors:

Louis E. Henderson, Mt. Airy, MD (US);

Larry O. Arthur, Walkersville, MD (US);

William G. Rice, Frederick, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12H 7/04 (2006.01); C12H 7/06 (2006.01); C07C 321/00 (2006.01); C07D 207/444 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides several classes of compounds which can be used to inactivate retroviruses, such as HIV-1, by attacking the CCHC zinc fingers of the viral nucleocapsid protein and ejecting the zinc therefrom. In addition, kits for identifying compounds that can react with CCHC zinc fingers of the nucleocapsid proteins of a large number of different retroviruses have also been developed. The kits of the present invention describe a set of specific tests and reagents that can be used to screen and identify compounds based on their ability to react with and disrupt retroviral zinc fingers in the viral NC proteins and, in turn, inactivate the retrovirus of interest.


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