The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2006
Filed:
Oct. 21, 1999
Applicants:
Masayuki Tsuchiya, Gotemba, JP;
Toshihiko Ohtomo, Gotemba, JP;
Yasuhiro Sugamata, Gotemba, JP;
Kunihiro Matsumoto, Nagoya, JP;
Inventors:
Masayuki Tsuchiya, Gotemba, JP;
Toshihiko Ohtomo, Gotemba, JP;
Yasuhiro Sugamata, Gotemba, JP;
Kunihiro Matsumoto, Nagoya, JP;
Assignee:
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/48 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to methods of screening for compounds that inhibit signal transduction by inflammatory cytokines. The methods include providing a sample that contains a TAK1 and a TAB1; contacting the sample with a compound; detecting binding between the TAK1 and the TAB1; and selecting the compound if binding between the TAK1 and TAB1 is inhibited in the sample compared to a control.