The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2006

Filed:

Mar. 31, 2003
Applicants:

Ghulam Nabi Qazi, Jammu, IN;

OM Parkash Suri, Jammu, IN;

Kasturi Lal Bedi, Jammu, IN;

Krishan Avtar Suri, Jammu, IN;

Bishan Datt Gupta, Jammu, IN;

Bupinder Singh Jaggi, Jammu, IN;

Bal Krishan Kapahi, Jammu, IN;

Naresh Kumar Satti, Jammu, IN;

Musarat Amina, Jammu, IN;

Bal Krishan Chandan, Jammu, IN;

Neelam Sharma, Jammu, IN;

Gurdarshan Singh, Jammu, IN;

Inventors:

Ghulam Nabi Qazi, Jammu, IN;

Om Parkash Suri, Jammu, IN;

Kasturi Lal Bedi, Jammu, IN;

Krishan Avtar Suri, Jammu, IN;

Bishan Datt Gupta, Jammu, IN;

Bupinder Singh Jaggi, Jammu, IN;

Bal Krishan Kapahi, Jammu, IN;

Naresh Kumar Satti, Jammu, IN;

Musarat Amina, Jammu, IN;

Bal Krishan Chandan, Jammu, IN;

Neelam Sharma, Jammu, IN;

Gurdarshan Singh, Jammu, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/78 (2006.01); A61K 31/70 (2006.01); A61K 31/33 (2006.01); A61K 31/555 (2006.01); A61K 31/05 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process of isolation of pure Acteoside of high hepatoprotection from plant, said process comprising steps of drying aerial parts of the plant, grounding the dried parts into powder, percolating the powder with water or ethanol for 3-4 times to obtain an extract, filtering the extract for clearing of suspended particles to obtain supernatant, drying the supernatant at about 45 to 55° C. to obtain a residue, fractionating the residue with chloroform, ethyl acetate, and butanol successively, subjecting butanol fraction to adsorption chromatography of SiOafter adding methanol to the fraction, charging the adsorbed fraction to glass column, eluting the column with solvents of increasing polarity of methanol:chloroform to obtain further fractions and repeating the process one more time, subjecting the fractions to column chromatography to obtain fractions, concentrating the fractions under reduced pressure to obtain acteoside as residue; and a method of effectively hepatoprotecting a subject using pure Acteoside from plant, said method comprising steps of administering appropriate low-dose of the acteoside to the subject.


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