The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2006
Filed:
Jun. 30, 2000
Samatha J. Busfield, Maddington, AU;
Jean-luc Villeval, Needham, MA (US);
Martine Jandrot-perrus, Vanves, FR;
William Vainchencker, Paris, FR;
Davinder Singh Gill, Burlington, MA (US);
Ming Diana Qian, Cambridge, MA (US);
Gillian Kingsbury, W. Roxbury, MA (US);
Samatha J. Busfield, Maddington, AU;
Jean-Luc Villeval, Needham, MA (US);
Martine Jandrot-Perrus, Vanves, FR;
William Vainchencker, Paris, FR;
Davinder Singh Gill, Burlington, MA (US);
Ming Diana Qian, Cambridge, MA (US);
Gillian Kingsbury, W. Roxbury, MA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein V1, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the exposure vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.