The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2006
Filed:
Feb. 14, 2001
Carl P. Decicco, Kennett Square, PA (US);
David J. Nelson, Newark, DE (US);
John A. Barrett, Groton, MA (US);
Alan P. Carpenter Jr., Carlisle, MA (US);
Jingwu Duan, Newark, DE (US);
Milind Rajopadhye, Westford, MA (US);
Carl P. Decicco, Kennett Square, PA (US);
David J. Nelson, Newark, DE (US);
John A. Barrett, Groton, MA (US);
Alan P. Carpenter Jr., Carlisle, MA (US);
Jingwu Duan, Newark, DE (US);
Milind Rajopadhye, Westford, MA (US);
Bristol-Myers Squibb Pharma Company, Princeton, NJ (US);
Abstract
Thus the present invention describes novel compounds comprising 1-10 targeting moieties; a chelator (Ch); and 0-1 linking groups (Ln) between the targeting moiety and chelator; wherein the targeting moiety is a matrix metalloproteinase inhibitor; and wherein the chelator is capable of conjugating to a cytotoxic radioisotope. The present invention also provides novel compositions of the compounds of the invention, kits and their uses in treatment of diseases associated with MMPs.