The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2006
Filed:
Jan. 09, 2001
Alan Wellington Faull, Macclesfield, GB;
Jason Grant Kettle, Macclesfield, GB;
Alan Wellington Faull, Macclesfield, GB;
Jason Grant Kettle, Macclesfield, GB;
AstraZeneca AB, Sodertalje, SE;
Abstract
A compound of Formula I,wherein: Ris hydrogen, halo, methyl, ethyl or methoxy; Ris hydrogen, halo, methyl, ethyl or methoxy; Ris a halo group, lower alkyl, lower alkenyl, lower alkynyl, alkoxy, trifluoromethyl, nitro, cyano, trifluoromethoxy, C(O)R, or S(O)Rwhere n is 0, 1 or 2 and Ris an alkyl group; Ris a halo, trifluoromethyl, methylthio, methoxy, trifluoromethoxy or lower alkyl, lower alkenyl or lower alkynyl or CORwhere Ris lower alkyl; Ris hydrogen, halo, lower alkyl, lower alkenyl, lower alkynyl or CORwhere Ris lower alkyl; provided that when Ris hydrogen, halo or methoxy, Ris hydrogen, halo, methyl, ethyl or methoxy, Rand Rare both hydrogen, and one of Ror Ris not halo or trifluoromethyl; or a pharmaceutically acceptable salt or prodrug thereof. These compounds have useful activity for the treatment of inflammatory disease, specifically in antagonizing an MCP-1 mediated effect in a warm-blooded animal such as a human being.