The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2006
Filed:
Feb. 13, 2004
Zhonghui LU, Wilmington, DE (US);
Thomas P. Maduskuie, Jr., Wilmington, DE (US);
Matthew E. Voss, Lincoln Univ., PA (US);
Chu-biao Xue, Hockessin, DE (US);
Jingwu Duan, Newark, DE (US);
Gregory Ott, Philadelphia, PA (US);
Lihua Chen, Wilmington, DE (US);
Carl Decicco, Kennett Square, PA (US);
Zhonghui Lu, Wilmington, DE (US);
Thomas P. Maduskuie, Jr., Wilmington, DE (US);
Matthew E. Voss, Lincoln Univ., PA (US);
Chu-Biao Xue, Hockessin, DE (US);
Jingwu Duan, Newark, DE (US);
Gregory Ott, Philadelphia, PA (US);
Lihua Chen, Wilmington, DE (US);
Carl Decicco, Kennett Square, PA (US);
Bristol-Myers Squibb Pharma Company, Princeton, NJ (US);
Abstract
The present application describes novel cyclic β-amino acid derivatives of formula I:or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NR, and S(O), and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease and/or as TNF-α inhibitors.