The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2006

Filed:

May. 31, 2002
Applicants:

John M. Brown, Redwood City, CA (US);

Shie-chau Liu, Redwood City, CA (US);

Amato J. Giaccia, Stanford, CA (US);

Nigel P. Minton, Salisbury, GB;

Inventors:

John M. Brown, Redwood City, CA (US);

Shie-Chau Liu, Redwood City, CA (US);

Amato J. Giaccia, Stanford, CA (US);

Nigel P. Minton, Salisbury, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); A01N 63/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Recombinant anaerobic bacterial compositions that under anaerobic conditions present in a solid tumor and produce an enzyme capable of catalyzing the conversion of a prodrug to its cytotoxic product in situ are described. Methods of treating tumors using the composition are also described.


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