The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6984399 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 10, 2006

Filed:

Dec. 19, 2003
Applicants:

Zlatko Pflaum, Domzale, SI;

Mateja Salobir, Ljubljana, SI;

Zdenka Jerala, Mavcice, SI;

Aleksander Resman, Ljubljana, SI;

Inventors:

Zlatko Pflaum, Domzale, SI;

Mateja Salobir, Ljubljana, SI;

Zdenka Jerala, Mavcice, SI;

Aleksander Resman, Ljubljana, SI;

Assignee:

Lek Pharmaceuticals d.d., Ljubjana, SI;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/28 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a novel solid pharmaceutical formulation containing lovastatin and simvastatin, respectively, with a particle size D(0.9) between 15 and 100 μm and a specific particle surface area between 1 and 4 m/g, and to the process for its preparation. The present invention also relates to the method for production of lovastatin and simvastatin with the size of crystals which are suitable for the preparation of the pharmaceutical formulation of the present invention. The novel solid pharmaceutical formulation is useful for treating hypercholesterolemia and hyperlipidemia.


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