The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2006

Filed:

Jul. 27, 2000
Applicants:

Man Sung CO, Cupertino, CA (US);

Maximiliano Vasquez, Palo Alto, CA (US);

Beatriz Carreno, Acton, MA (US);

Abbie Cheryl Celniker, Newton, MA (US);

Mary Collins, Natick, MA (US);

Samuel Goldman, Acton, MA (US);

Gary S. Gray, Brookline, MA (US);

Andrea Knight, Hampton, NH (US);

Denise O'hara, Reading, MA (US);

Bonita Rup, Reading, MA (US);

Geertruida M. Veldman, Sudbury, MA (US);

Inventors:

Man Sung Co, Cupertino, CA (US);

Maximiliano Vasquez, Palo Alto, CA (US);

Beatriz Carreno, Acton, MA (US);

Abbie Cheryl Celniker, Newton, MA (US);

Mary Collins, Natick, MA (US);

Samuel Goldman, Acton, MA (US);

Gary S. Gray, Brookline, MA (US);

Andrea Knight, Hampton, NH (US);

Denise O'Hara, Reading, MA (US);

Bonita Rup, Reading, MA (US);

Geertruida M. Veldman, Sudbury, MA (US);

Assignee:

Genetics Institute, LLC, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 35/26 (2006.01); A61K 35/28 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.


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