The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2006
Filed:
Dec. 18, 2003
Jacques Bourget, Vitry sur Seine, FR;
Marc Antoine Perrin, Jouy en Josas, FR;
Serge Mignani, Chatenay Malabry, FR;
Bernd Janocha, Wiesbaden, DE;
Michel Cheve, Soisy sur Seine, FR;
Carole Neves, Paris, FR;
Pascal Billot, Montreuil, FR;
Michel Tabart, La Novrille, FR;
Sylvaine Lafont, Trevoux, FR;
Jacques Bourget, Vitry sur Seine, FR;
Marc Antoine Perrin, Jouy en Josas, FR;
Serge Mignani, Chatenay Malabry, FR;
Bernd Janocha, Wiesbaden, DE;
Michel Cheve, Soisy sur Seine, FR;
Carole Neves, Paris, FR;
Pascal Billot, Montreuil, FR;
Michel Tabart, La Novrille, FR;
Sylvaine Lafont, Trevoux, FR;
Aventis Pharma S.A., Antony, FR;
Abstract
The present invention comprises crystalline forms of 3R,4R)-4-[3-(S)-hydroxy-3-(6-methoxyquinolin-4-yl)propyl]-1-[2-(2-thienylthio)ethyl]piperidine-3-carboxylic acid, represented by the structure:and as characterized herein by powder X-ray diffraction patterns as form A and form B, processes for preparing form A from the purified amorphous form of (3R,4R)-4-[3-(S)-hydroxy-3-(6-methoxyquinolin-4-yl)propyl]-1-[2-(2-thienylthio)ethyl]piperidine-3-carboxylic acid, a processes for preparing form A by heating monohydrated form C of (3R,4R)-4-[3-(S)-hydroxy-3-(6-methoxyquinolin-4-yl)propyl]-1-[2-(2-thienylthio)ethyl]piperidine-3-carboxylic acid, a pharmaceutical composition comprising form A, a pharmaceutical composition comprising form A and form B or monohydrated form C, a pharmaceutical composition comprising form A, form B and monohydrated form C, a method for treating a bacterial infection with form A, a method for treating a bacterial infection with form A and form B or monohydrated form C, and a method for treating a bacterial infection with form A and form B and monohydrated form C.