The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2006
Filed:
Jul. 12, 2001
David John Smith, Naantali, FI;
Ferenc Fülöp, Szeged, HU;
Marjo Pihlavisto, Kaarina, FI;
László Lázár, Szeged, HU;
Sakari Alaranta, Raisio, FI;
Petri Vainio, Turku, FI;
Zsolt Szakonyi, Szeged, HU;
David John Smith, Naantali, FI;
Ferenc Fülöp, Szeged, HU;
Marjo Pihlavisto, Kaarina, FI;
László Lázár, Szeged, HU;
Sakari Alaranta, Raisio, FI;
Petri Vainio, Turku, FI;
Zsolt Szakonyi, Szeged, HU;
Biotie Therapies Corp., Turku, FI;
Abstract
The present invention is directed to carbocyclic hydrazino compounds that function as inhibitors of copper-containing amine oxidases commonly known as semicarbazide-sensitive amine oxidases (SSAO), including the human SSAO known as Vascular Adhesion Protein-I (VAP-1). These SSAO inhibitors have therapeutic utility as drugs to treat conditions and diseases including, but not limited to, a number of inflammatory conditions and diseases (in particular chronic inflammatory conditions such as chronic arthritis, inflammatory bowel diseases, and chronic skin dermatoses), diseases related to carbohydrate metabolism and to aberrations in adipocyte differentiation or function and smooth muscle cell function, and vascular diseases. The novel compounds have the general formula:or a pharmaceutically acceptable solvate, hydrate, or salt thereof wherein Rto Rare as defined herein.