The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2006
Filed:
Apr. 26, 2001
Hideo Hashimoto, Kobe, JP;
Tadashi Urai, Takatsuki, JP;
Hideo Hashimoto, Kobe, JP;
Tadashi Urai, Takatsuki, JP;
Takeda Pharmaceutical Company Limited, Osaka, JP;
Abstract
The present invention relates to a production method of an optically active form of a compound represented by formula (II)wherein ring A is a benzene ring optionally having substituent(s); Ris H, a hydrocarbon group optionally having substituent(s), an acyl group or an acyloxy group; R, Rand Rare each H, an alkyl group optionally having substituent(s), an alkoxy group optionally having substituent(s) or an amino group optionally having substituent(s); X is N or CH; Y is N or CH; and * shows an asymmetric center, or a salt thereof, which includes reacting a compound represented by the formula (I)wherein each symbol is as defined above, or a salt thereof, with an excess amount of an oxidizing agent in the presence of a catalyst for asymmetric induction, and provides an efficient production method of an optically active sulfoxide derivative in high yield on an industrial large scale by a convenient method, while achieving an extremely high enantiomer excess.