The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2006

Filed:

Apr. 15, 2002
Applicants:

Hitoshi Oinuma, Ibaraki, JP;

Norihito Ohi, Ibaraki, JP;

Nobuaki Sato, Ibaraki, JP;

Motohiro Soejima, Ibaraki, JP;

Hidenori Seshimo, Saitama, JP;

Taro Terauchi, Ibaraki, JP;

Takashi Doko, Ibaraki, JP;

Naohiro Kohmura, Ibaraki, JP;

Inventors:

Hitoshi Oinuma, Ibaraki, JP;

Norihito Ohi, Ibaraki, JP;

Nobuaki Sato, Ibaraki, JP;

Motohiro Soejima, Ibaraki, JP;

Hidenori Seshimo, Saitama, JP;

Taro Terauchi, Ibaraki, JP;

Takashi Doko, Ibaraki, JP;

Naohiro Kohmura, Ibaraki, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 23/56 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a novel 1H-indazole compound having an excellent JNK inhibitory action. More specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them.Wherein Ris a C-Caromatic cyclic hydrocarbon group etc.; R, Rand Reach independently represent a hydrogen atom, a halogen atom, a cyano group etc.; L is a single bond, or a C-Calkylene group etc.; X is a single bond, or a group represented by —CO—NH— or —NH—CO—, etc.; and Y is a C-Ccycloalkyl group, a C-Caromatic cyclic hydrocarbon group or a 5- to 14-membered aromatic heterocyclic group etc.


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