The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2006
Filed:
Jun. 04, 2002
Eugene R. Hickey, Danbury, CT (US);
Younes Bekkali, Danbury, CT (US);
Usha R. Patel, Brookfield, CT (US);
Denice Mary Spero, West Redding, CT (US);
David S. Thomson, Ridgefield, CT (US);
Erick Richard Roush Young, Danbury, CT (US);
Eugene R. Hickey, Danbury, CT (US);
Younes Bekkali, Danbury, CT (US);
Usha R. Patel, Brookfield, CT (US);
Denice Mary Spero, West Redding, CT (US);
David S. Thomson, Ridgefield, CT (US);
Erick Richard Roush Young, Danbury, CT (US);
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT (US);
Abstract
Disclosed are novel nitrile compounds of formula (I) further defined herein, which compounds are useful as reversible inhibitors of cysteine proteases such as cathepsin K, S, F, L and B. These compounds are useful for treating diseases and pathological conditions exacerbated by these proteases such as, but not limited to, osteoporosis, rheumatoid arthritis, multiple sclerosis, asthma and other autoimmune diseases, Alzheimer's disease, atherosclerosis. Also disclosed are processes for making such novel compounds.