The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2006
Filed:
Oct. 15, 2002
Gary Posner, Baltimore, MD (US);
Mehmet Kahraman, Baltimore, MD (US);
Heung Bae Jeon, Baltimore, MD (US);
Jay A. White, Ontario, CA;
Glenville Jones, Ontario, CA;
Bethany Halford, Baltimore, MD (US);
Gary Posner, Baltimore, MD (US);
Mehmet Kahraman, Baltimore, MD (US);
Heung Bae Jeon, Baltimore, MD (US);
Jay A. White, Ontario, CA;
Glenville Jones, Ontario, CA;
Bethany Halford, Baltimore, MD (US);
Cytochroma Inc., Markham, CA;
Johns Hopkins University, Baltimore, MD (US);
Abstract
The present invention provides novel 16-ene-C25-oxime and 16-ene-C-25-oxime ether analogs of 1α,25-dihydroxy vitamin D, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the compound of Formula I are useful for treating diseases which benefit from a modulation of the levels of 1α,25-dihydroxy vitamin D, for example, cell-proliferative disorders.