The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2006

Filed:

Jun. 11, 2002
Applicants:

Anima Ghosal, Edison, NJ (US);

Shmuel Zbaida, East Brunswick, NJ (US);

Swapan K. Chowdhury, Warren, NJ (US);

Robert M. Iannucci, Hampton, NJ (US);

Wenqing Feng, Chatham, NJ (US);

Kevin B. Alton, Cedar Knolls, NJ (US);

James E. Patrick, Belle Mead, NJ (US);

Harry R. Davis, Berkeley Heights, NJ (US);

Inventors:

Anima Ghosal, Edison, NJ (US);

Shmuel Zbaida, East Brunswick, NJ (US);

Swapan K. Chowdhury, Warren, NJ (US);

Robert M. Iannucci, Hampton, NJ (US);

Wenqing Feng, Chatham, NJ (US);

Kevin B. Alton, Cedar Knolls, NJ (US);

James E. Patrick, Belle Mead, NJ (US);

Harry R. Davis, Berkeley Heights, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7056 (2006.01); A61K 31/397 (2006.01); A61K 31/675 (2006.01); C07H 17/02 (2006.01); C07D 25/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Hypocholesterolemic substituted 2-azetidinone compounds of the formula:are disclosed, as well as a methods of lowering cholesterol by administering said compounds, pharmaceutical compositions containing them, and the combination of a substituted 2-azetidinone cholesterol-lowering agent and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis.


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