The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2005

Filed:

Mar. 04, 2002
Applicants:

Guixue Yu, Lawrenceville, NJ (US);

John Macor, Guilford, CT (US);

Timothy Herpin, Princeton, NJ (US);

R. Michael Lawrence, Yardley, PA (US);

George C. Morton, Collegeville, PA (US);

Rejean Ruel, Saint-Lambert, CA;

Graham S. Poindexter, Old Saybrook, CT (US);

Edward H. Ruediger, Greenfield Park, CA;

Carl Thibault, Mascouche, CA;

Inventors:

Guixue Yu, Lawrenceville, NJ (US);

John Macor, Guilford, CT (US);

Timothy Herpin, Princeton, NJ (US);

R. Michael Lawrence, Yardley, PA (US);

George C. Morton, Collegeville, PA (US);

Rejean Ruel, Saint-Lambert, CA;

Graham S. Poindexter, Old Saybrook, CT (US);

Edward H. Ruediger, Greenfield Park, CA;

Carl Thibault, Mascouche, CA;

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/445 ; C07D401/14 ;
U.S. Cl.
CPC ...
Abstract

Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates and prodrugs thereof,in which E isX is N or CH, W is —NRR, —NRC(═O)R, —NRCOR, —OR, or a heteroaryl or heterocyclo group as defined in the specification, and Rthrough R, R, R, R, R, x, y, and z are as defined in the specification, are useful as modulaters of melanocortin receptors, particularly MC-1R and MC-4R.


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