The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2005
Filed:
Feb. 25, 2002
Jay D. Hunt, Slidell, LA (US);
Haydee E. Bazan, New Orleans, LA (US);
Victor L. Marcheselli, Covington, LA (US);
Julio Alvarez Builla Gomez, Madrid, ES;
Nicholas G. Bazan, New Orleans, LA (US);
Jay D. Hunt, Slidell, LA (US);
Haydee E. Bazan, New Orleans, LA (US);
Victor L. Marcheselli, Covington, LA (US);
Julio Alvarez Builla Gomez, Madrid, ES;
Nicholas G. Bazan, New Orleans, LA (US);
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US);
Abstract
A novel use of platelet-activating factor antagonists that bind to intracellular PAF binding sites such as BN-50730 (tetrahedra-4,7,8,10 methyl-1 (chloro-1 phenyl)-6 (methoxy-4 phenyl-carbamoyl)-9 pyrido [4',3′-4,5] thieno [3,2-f] triazolo-1,2,4 [4,3-a] diazepine-1,4) has been discovered. These intracellular-binding platelet-activating factor antagonists were found to inhibit both in vivo and in vitro tumor growth and angiogenesis where the angiogenesis is stimulated by basic fibroblast growth factor.