The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2005

Filed:

May. 18, 2004
Applicants:

Robert Edward Morris, Eire, IR;

Peter John Sadler, Penicuik, GB;

Haimei Chen, Edinburgh, GB;

Duncan Jodrell, Edinburgh, GB;

Inventors:

Robert Edward Morris, Eire, IR;

Peter John Sadler, Penicuik, GB;

Haimei Chen, Edinburgh, GB;

Duncan Jodrell, Edinburgh, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F017/02 ; A61K031/295 ; A61K031/4409 ; A61P035/00 ;
U.S. Cl.
CPC ...
Abstract

Ruthenium (II) compounds of the formula:wherein: Ris —COCH; R, R, R, Rand Rindependently represent H, alkyl, cylcoalkyl, —COR', aryl or alkylaryl, which latter two groups are optionally substituted on the aromatic ring; R′ represents alkyl, cylcoalkyl, aryl or alkaryl; X is halo, HO, (R′)(R″)SO, R′COor (R′)(R″)C═O, where R″ represents alkyl, cylcoalkyl, aryl or alkaryl; Y is a counterion; m is 0 or 1; q is 1, 2 or 3; C′ is Cto Calkylene, optionally substituted in or on the alkylene chain, bound to two A groups; p is 0 or 1 and r is 1 when p is 0 and r is 2 when p is 1; and A and B are: each independently R—CN, where R″ represents alkyl or cycloalkyl; or B is halo and A is 4-substitued pyridine; or p is 0, A is NRRand B is NRRwherein R, R, Rand Rindependently represent H, or alkyl, and A and B are linked by an alkylene chain, optionally substituted in or on the alkylene chain; or p is 1, A is NRand B is NRR, wherein R, Rand Rare as previously defined, and A and B are linked by an alkylene chain, optionally substituted are described.


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