The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2005

Filed:

Sep. 05, 2000
Applicants:

Suman Preet Singh Khanuja, Lucknow, IN;

Sushil Kumar, Lucknow, IN;

Jai Shankar Arya, Lucknow, IN;

Ajit Kumar Shasany, Lucknow, IN;

Monika Singh, Lucknow, IN;

Soumya Awasthi, Lucknow, IN;

Subhas Chandra Gupta, Lucknow, IN;

Mahendra Pandurang Darokar, Lucknow, IN;

Laiq Ur Rahman, Lucknow, IN;

Inventors:

Suman Preet Singh Khanuja, Lucknow, IN;

Sushil Kumar, Lucknow, IN;

Jai Shankar Arya, Lucknow, IN;

Ajit Kumar Shasany, Lucknow, IN;

Monika Singh, Lucknow, IN;

Soumya Awasthi, Lucknow, IN;

Subhas Chandra Gupta, Lucknow, IN;

Mahendra Pandurang Darokar, Lucknow, IN;

Laiq Ur Rahman, Lucknow, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K035/78 ;
U.S. Cl.
CPC ...
Abstract

The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside 'glycyrrhizin' as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the absorption/uptake of antibiotics and other molecules across the cell membrane in plant and animal cells as well as Gram-positive and Gram-negative bacteria and therefore can be used as a drug facilitator or bioenhancer molecule to increase the affectivity of drugs and nutraceutical agents. The compound having no antimicrobial or cytotoxic activity of its own, is a safe candidate to reduce the drug dosage towards circumventing the problem of drug resistance and the other side effects in anti-infective and anti-cancer therapies.


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