The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 27, 2005

Filed:

Sep. 11, 2000
Applicants:

Mary Bendig, Vesenaz, CH;

Tim Jones, Babraham, GB;

Koen Hellendoorn, Newmarket, GB;

Inventors:

Mary Bendig, Vesenaz, CH;

Tim Jones, Babraham, GB;

Koen Hellendoorn, Newmarket, GB;

Assignee:

The Dow Chemical Company, Midland, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K039/12 ; A61K048/00 ;
U.S. Cl.
CPC ...
Abstract

Mucin peptide epitopes are inserted into the coat protein of a plant virus (e.g., a comovirus such as CPMV) having a beta-barrel structure at an immunogenically effective site, such as in a loop connecting beta sheets or at/near the C-terminus. The resulting chimaeric virus particles are extremely immunogenic, giving better results than KLH conjugation and not requiring the addition of exogenous adjuvant. They are effective at mucosal surfaces, particularly when administered intranasally.


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