The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2005

Filed:

Apr. 02, 2001
Applicants:

Tetsuya Ikemoto, Osaka, JP;

Nobuhiro Arai, Osaka, JP;

Masami Igi, Osaka, JP;

Inventors:

Tetsuya Ikemoto, Osaka, JP;

Nobuhiro Arai, Osaka, JP;

Masami Igi, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D307/78 ; A61K031/343 ;
U.S. Cl.
CPC ...
Abstract

According to the present invention, citalopram hydrobromide dissolved in a solvent containing at least one member selected from the group consisting of alcohol having 1-3 carbon atoms, water and acetone is crystallized or recrystallized while controlling the cooling rate, thereby to 1) provide an industrial method for crystallizing citalopram hydrobromide, which enables easy control of the crystal characteristics, such as particle size, particle size distribution and aspect ratio and the like of the crystal, and 2) provide citalopram hydrobromide crystal having crystal characteristics useful as a pharmaceutical bulk.


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