The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 20, 2005

Filed:

Apr. 21, 2000
Applicants:

Boris Belotserkovskii, Mountain View, CA (US);

Gurucharan Reddy, Fremont, CA (US);

David A. Zarling, Menlo Park, CA (US);

Inventors:

Boris Belotserkovskii, Mountain View, CA (US);

Gurucharan Reddy, Fremont, CA (US);

David A. Zarling, Menlo Park, CA (US);

Assignee:

Invitrogen Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/04 ;
U.S. Cl.
CPC ...
Abstract

The invention relates to methods for inhibiting, cloning, modifying or labelling an endogenous DNA sequence using compositions comprising recombinases in combination with exogenous polynucleotides containing 'anchoring' or 'locking' sequences. The anchoring sequences serve to stabilize structures formed by the exogenous polynucleotides and the endogenous DNA. The stabilized structure thus can either serve to regulate gene transcription or replication, or can allow the endogenous sequences to be labelled or pulled out, i.e. cloned, or modified.


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