The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2005
Filed:
Oct. 01, 2002
T. G. Murali Dhar, Newtown, PA (US);
Dominique Potin, Epone, FR;
Magali Jeannine Blandine Maillet, Suresnes, FR;
Michele Launay, Rueil Malmaison, FR;
Eric Antoine Nicolai, Rueil Malmaison, FR;
Edwin J. Iwanowicz, Cranbury, NJ (US);
T. G. Murali Dhar, Newtown, PA (US);
Dominique Potin, Epone, FR;
Magali Jeannine Blandine Maillet, Suresnes, FR;
Michele Launay, Rueil Malmaison, FR;
Eric Antoine Nicolai, Rueil Malmaison, FR;
Edwin J. Iwanowicz, Cranbury, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
CEREP SA, Rueil-Malmaison, FR;
Abstract
Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof,are useful as inhibitors of LFA-1/ICAM and as anti-inflammatory agents, wherein L and K are O or S; Z is N or CR; Ar is an optionally-substituted aryl or heteroaryl; G is a linker attached to T or M or is absent; J, M and T are selected to define a three to six membered saturated or partially unsaturated non-aromatic ring; and R,R, R, and Rare as defined in the specification.