The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2005
Filed:
May. 19, 2000
Noboru Kaneko, Tokyo, JP;
Kazuhito Nishio, Chiba, JP;
Takashi Nakamura, Nagasaki, JP;
Noboru Kaneko, , JP;
Abstract
The present invention relates to use of compounds represented by the following general formula [1] or salts or prodrugs thereof:[where Rrepresents hydrogen atom or lower alkoxy group; Rrepresents hydrogen atom, lower alkoxy group, optionally substituted phenyl group,(where Rrepresents acyl group); X represents —CO— or —CH—; and n-represents 1 or 2], as drugs for overcoming a resistance to anticancer drugs or drugs for enhancing an effect of anticancer drugs. The compounds represented by the general formula [1] have not only a function of overcoming the resistance to various anticancer drugs but also a function of enhancing the effect of various anticancer drugs to anticancer-drug sensitive cells. Thus, these compounds have excellent effects on resistant cells and also on sensitive cells, and in particular effective in the treatment of a cancer having an acquired resistance to an anticancer drug.