The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2005
Filed:
Sep. 17, 2001
Applicant:
Tetsuji Okamoto, Hiroshima, JP;
Inventor:
Tetsuji Okamoto, Hiroshima, JP;
Assignee:
Zeria Pharmaceutical Co., Ltd., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C12Q001/68 ; C12P019/34 ; C07H021/04 ; C12N005/10 ;
U.S. Cl.
CPC ...
Abstract
There is provided a method of testing squamous epithelial cells and a method of screening therapeutic agents for squamous cell carcinoma. That the base guanine at position 2128 (exon 17) of the FGFR3 gene is mutated to thymine in the cells of squamous cell carcinoma, or that the cells of squamous cell carcinoma produce an FGFR3 protein in which the amino acid glycine at position 697 is mutated to cysteine is utilized to facilitate the diagnosis and treatment of squamous cell carcinoma.