The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2005
Filed:
Jun. 18, 2003
Jaan Noolandi, Palo Alto, CA (US);
Christopher Ta, Palo Alto, CA (US);
Philip Huie, Jr., Cupertino, CA (US);
Alan J. Smith, Redwood City, CA (US);
Robert Waymouth, Stanford, CA (US);
Mark Blumenkranz, Portola Valley, CA (US);
Jaan Noolandi, Palo Alto, CA (US);
Christopher Ta, Palo Alto, CA (US);
Philip Huie, Jr., Cupertino, CA (US);
Alan J. Smith, Redwood City, CA (US);
Robert Waymouth, Stanford, CA (US);
Mark Blumenkranz, Portola Valley, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Abstract
The invention provides implants suitable for use as an artificial cornea, and methods for making and using such implants. Artificial corneas having features of the invention may be two-phase artificial corneas, or may be three phase artificial corneas. These artificial corneas have a flexible, optically clear central core and a hydrophilic, porous skirt, both of which are biocompatible and allow for tissue integration. A three-phase artificial cornea will further have an interface region between the core and skirt. The artificial corneas have a high degree of ocular tolerance, and allow for tissue integration into the skirt and for epithelial cell growth over the surface of the prosthesis. The use of biocompatible material avoids the risk of disease transmission inherent with corneal transplants, and acts to minimize post-operative inflammation and so to reduce the chance or severity of tissue necrosis following implantation of the synthetic cornea onto a host eye.