The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2005
Filed:
Dec. 23, 2002
Michiya Okada, Mito, JP;
Tsuyoshi Wakuda, Hitachi, JP;
Shigeru Kakugawa, Hitachi, JP;
Hiroshi Morita, Hitachi, JP;
Katsuzou Aihara, Mito, JP;
Michiya Okada, Mito, JP;
Tsuyoshi Wakuda, Hitachi, JP;
Shigeru Kakugawa, Hitachi, JP;
Hiroshi Morita, Hitachi, JP;
Katsuzou Aihara, Mito, JP;
Hitachi, Ltd., Tokyo, JP;
Abstract
It is possible to grasp the behavior of a protein in a cell by realizing a nuclear magnetic resonance imaging method having spatial resolutions on the scale of a cell, and to provide an industrial measure for developing a high-quality protein utilizing this technology. In order to realize spatial resolutions in the order of one-tenth the size of a cell, a supersensitive measurement is realized by the combination of a solenoid detector coil and a high magnetic field NMR of not less than 14 Tesla, which has not been used so far. It is combined with the magnetic field uniformity of 0.001 ppm, so that the supersensitive NMR imaging of 0.5 μm, which has been impossible heretofore, is realized. The physico-chemical behavior of protein molecules can be easily clarified, and thus the bioinfomatic network or the process of metabolism of the cell can be brought out.