The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2005

Filed:

Aug. 23, 2002
Applicants:

Kari Alitalo, Helsinki, FI;

Carl-henrik Heldin, Uppsala, SE;

Olli Leppänen, Uppsala, SE;

Arne Östman, Uppsala, SE;

Seppo Ylā-herttuala, Vuirela, FI;

Inventors:

Kari Alitalo, Helsinki, FI;

Carl-Henrik Heldin, Uppsala, SE;

Olli Leppänen, Uppsala, SE;

Arne Östman, Uppsala, SE;

Seppo Ylā-Herttuala, Vuirela, FI;

Assignees:

Licentia Ltd., Helsinki, FI;

Ludwig Institiute for Cancer Research, New York, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/497 ; A61K009/08 ; A61K009/14 ; A61K009/20 ; A61K009/48 ;
U.S. Cl.
CPC ...
Abstract

The invention relates to a combination of (a) an inhibitor of platelet-derived growth factor (PDGF) activity and (b) a vector for vascular endothelial growth factor (VEGF-, especially VEGF-C) gene transfer, a pharmaceutical preparation comprising (a) and (b) in combination together with a pharmaceutically acceptable carrier material; a product comprising (a) and (b) as defined above and optionally a pharmaceutically acceptable carrier material, for simultaneous, chronologically staggered or separate use; a method of administering or the use of said combination or product for the treatment of endothelial damage; and/or to the use of (a) and (b) for the manufacture of said pharmaceutical preparation or product for the treatment of endothelial damage.


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