The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 13, 2005

Filed:

Oct. 09, 2003
Applicants:

T G. Murali Dhar, Newtown, PA (US);

Dominique Potin, Epone, FR;

Magali Jeannine Blandine Maillet, Suresnes, FR;

Michele Launay, Rueil Malmaison, FR;

Eric Antoine Nicolai, Rueil Malmaison, FR;

Edwin J. Iwanowicz, San Diego, CA (US);

Inventors:

T G. Murali Dhar, Newtown, PA (US);

Dominique Potin, Epone, FR;

Magali Jeannine Blandine Maillet, Suresnes, FR;

Michele Launay, Rueil Malmaison, FR;

Eric Antoine Nicolai, Rueil Malmaison, FR;

Edwin J. Iwanowicz, San Diego, CA (US);

Assignees:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Cerep SA, Rueil-Malmaison, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/4188 ; A61K031/4184 ; A61K031/437 ; C07D235/26 ; C07D237/26 ;
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds having the formula (I):useful in treating inflammatory and immune diseases, in which K is O or S; Q is —C(═O)— or optionally substituted Calkylene; Ar is optionally-substituted aryl or heteroaryl; J, J, J, and Y are selected so that ring A is a five-to-six membered optionally-substituted cycloalkenyl or heterocyclo ring having 0 to 2 nitrogen heteroatoms; Z is N or C(R); and R, R, Rand Rare as defined in the specification.


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