The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 2005
Filed:
Dec. 30, 2003
Applicants:
Mark a Dombroski, Waterford, CT (US);
Allen J. Duplantier, Ledyard, CT (US);
Inventors:
Mark A Dombroski, Waterford, CT (US);
Allen J. Duplantier, Ledyard, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D253/075 ; C07D295/02 ; A61K031/53 ; A61K031/5377 ; A61P019/02 ;
U.S. Cl.
CPC ...
Abstract
The present invention provides benzamide inhibitors of the P2Xreceptor of the formula:wherein R-Rare as defined herein. The compounds of the invention are useful in the treatment of IL-1 mediated disorders, including, without limitation, inflammatory diseases such as osteoarthritis and rheumatoid arthritis; allergies, asthma, COPD, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.