The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2005
Filed:
Oct. 06, 2003
Alfred Binggeli, Binningen, CH;
Markus Boehringer, Moehlin, CH;
Uwe Grether, Loerrach, DE;
Hans Hilpert, Muenchenstein, CH;
Georges Hirth, Huningue, FR;
Hans-peter Maerki, Basel, CH;
Markus Meyer, Neuenburg, DE;
Peter Mohr, Basel, CH;
Fabienne Ricklin, Hombourg, FR;
Alfred Binggeli, Binningen, CH;
Markus Boehringer, Moehlin, CH;
Uwe Grether, Loerrach, DE;
Hans Hilpert, Muenchenstein, CH;
Georges Hirth, Huningue, FR;
Hans-Peter Maerki, Basel, CH;
Markus Meyer, Neuenburg, DE;
Peter Mohr, Basel, CH;
Fabienne Ricklin, Hombourg, FR;
Hoffman-La Roche Inc., Nutley, NJ (US);
Abstract
The present invention relates to compounds of formula (I)wherein wherein R, R, R, R, R, Rand n are as described herein. The compounds of the present invention can be used as medicaments for the treatment and/or prevention of diseases which are modulated by PPARα and/or PPARγ agonists. Examples of such diseases are diabetes, particularly non-insulin dependent diabetes mellitus, elevated blood pressure, increased lipid and cholesterol levels, atherosclerotic diseases, metabolic syndrome, endothelial dysfunction, procoagulant state, dyslipidemia, polycystic ovary syndrome, inflammatory diseases (such as e.g. crown disease, inflammatory bowel disease, collitis, pancreatitis, cholestasis/fibrosis of the liver, and diseases that have an inflammatory component such as e.g. Alzheimer's disease or impaired/improvable cognitive function) and proliferative diseases.