The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2005
Filed:
Jan. 30, 2004
Wesley Peter Blackaby, Buckhurst Hill, GB;
Simon Charles Goodacre, Benington, GB;
David James Hallett, Watford, GB;
Andrew Jennings, Sawbridgeworth, GB;
Richard Thomas Lewis, Bishops Stortford, GB;
Leslie Joseph Street, Little Hallingbury, GB;
Kevin Wilson, Bishops Stortford, GB;
Wesley Peter Blackaby, Buckhurst Hill, GB;
Simon Charles Goodacre, Benington, GB;
David James Hallett, Watford, GB;
Andrew Jennings, Sawbridgeworth, GB;
Richard Thomas Lewis, Bishops Stortford, GB;
Leslie Joseph Street, Little Hallingbury, GB;
Kevin Wilson, Bishops Stortford, GB;
Merck Sharp & Dohme Ltd., Hoddesdon, unknown;
Abstract
The present invention provides a compound of formula I, or an N-oxide thereof or a pharmaceutically acceptable salt thereof:wherein Xrepresents hydrogen, halogen, Calkyl, trifluoromethyl or Calkoxy; Xrepresents hydrogen or halogen; Z represents hydrogen, halogen, cyano, cyanomethyl, trifluoromethyl, nitro, hydroxy, hydroxy(C)alkyl, Calkoxy, Calkoxy(C)alkyl, trifluoromethoxy, trifluoromethylthio, trifluoromethanesulfinyl, formyl, Calkoxycarbonyl, oxopyrrolidinyl, or an optionally substituted aryl, heteroaryl or heteroaryl(C)alkoxy group; and Rrepresents aryl or heteroaryl, either of which groups may be optionally substituted; pharmaceutical compositions comprising it, its use in therapy and methods of treatment of anxiety and/or depression using it.