The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2005
Filed:
Nov. 14, 2001
Osamu Okamoto, Tsukuba, JP;
Hiroshi Kawamoto, Tsukuba, JP;
Kensuke Kobayashi, Tsukuba, JP;
Satoru Itoh, Tsubuka, JP;
Tetsuya Kato, Tsukuba, JP;
Izumi Yamamoto, Tsukuba, JP;
Yoshikazu Iwasawa, Tsukuba, JP;
Osamu Okamoto, Tsukuba, JP;
Hiroshi Kawamoto, Tsukuba, JP;
Kensuke Kobayashi, Tsukuba, JP;
Satoru Itoh, Tsubuka, JP;
Tetsuya Kato, Tsukuba, JP;
Izumi Yamamoto, Tsukuba, JP;
Yoshikazu Iwasawa, Tsukuba, JP;
Banyu Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
This invention relates to the compounds represented by a general formula [I]:[in which Aand Arepresent optionally fluorine-substituted methine or the like; B represents halogen, cyano, lower alkyl or the like; D represents optionally substituted heterocyclic group or the like; and G represents C-Caliphatic group such as alicyclic group]. These compounds inhibit nociceptin activities due to their high affinity to nociceptin receptor, and are useful as analgesic, antiobestic, corebral function improver, drugs for treatment of alzheimer's disease and dementia, remedies for schizophrenia and neurodegenerative diseases, antidepressant, remedies for diabetes insipidus, polyuria, hypotension and so on.