The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2005
Filed:
May. 17, 2002
Sylvie Bilodeau-goeseels, Lethbridge, CA;
Sushil Jacob John, Lethbridge, CA;
Leonard Brent Selinger, Lethbridge, CA;
Bernhard F. Benkel, Lethbridge, CA;
Sylvie Bilodeau-Goeseels, Lethbridge, CA;
Sushil Jacob John, Lethbridge, CA;
Leonard Brent Selinger, Lethbridge, CA;
Bernhard F. Benkel, Lethbridge, CA;
Abstract
The invention provides a nucleotide sequence of bovine epidermal growth factor (bEGF) and the deduced amino acid sequence of the encoded protein. The invention further provides the nucleotide sequence of mature bEGF and the deduced mature bEGF protein. The invention extends to homologous nucleic acids, proteins, and fragments functionally equivalent to the nucleotide sequence of the bEGF gene and bEGF protein, respectively. Bovine EGF may be expressed in microorganisms such asor, and plant hosts, such as potato. Activity of recombinant bEGF may be confirmed using a cell proliferation/DNA synthesis assay. Bovine EGF demonstrates utility in livestock and dairy productions as a supplement in farm animal feed to promote growth; to prevent or treat intestinal infections; to stimulate precocious maturation of gut cells to secrete an appropriate spectrum of digestive enzymes; and to increase nutrient absorption.