The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 22, 2005

Filed:

Aug. 27, 2004
Applicants:

Eishun Tsuchida, Tokyo, JP;

Shinji Takeoka, Tokyo, JP;

Yuji Teramura, Tokyo, JP;

Tomoyasu Atoji, Tokyo, JP;

Inventors:

Eishun Tsuchida, Tokyo, JP;

Shinji Takeoka, Tokyo, JP;

Yuji Teramura, Tokyo, JP;

Tomoyasu Atoji, Tokyo, JP;

Assignee:

Oxygenix Co., Ltd, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K038/44 ; A61K009/127 ;
U.S. Cl.
CPC ...
Abstract

An oxygen carrier system includes an artificial oxygen carrier including hemoglobin vesicles encapsulating hemoglobin and an intermediate electron mediator having a standard electrode potential of 0.05 V to 0.56 V (vs. the standard hydrogen electrode) in the vesicles, and a reducing agent which is added to an external aqueous phase of the hemoglobin vesicle to reduce methemoglobin when the hemoglobin encapsulated in the hemoglobin vesicle is oxidized to the methemoglobin. The reducing agent has, as an active component, at least one compound selected from the group consisting of a thiol compound and a reducing sugar.


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