The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2005

Filed:

Dec. 23, 2002
Applicants:

Samuel J. Danishefsky, Englewood, NJ (US);

Peter Bertinato, Old Lyme, CT (US);

Dai-shi Su, New York, NY (US);

Dongfang Meng, New York, NY (US);

Ting-chao Chou, Paramus, NJ (US);

Ted Kamenecka, New York, NY (US);

Erik J Sorensen, San Diego, CA (US);

Aaron Balog, New York, NY (US);

Kenneth A. Savin, New York, NY (US);

Scott Kuduk, Harleysville, PA (US);

Christina Harris, New York, NY (US);

Xiu-guo Zhang, New York, NY (US);

Joseph R. Bertino, Branford, CT (US);

Inventors:

Samuel J. Danishefsky, Englewood, NJ (US);

Peter Bertinato, Old Lyme, CT (US);

Dai-Shi Su, New York, NY (US);

DongFang Meng, New York, NY (US);

Ting-Chao Chou, Paramus, NJ (US);

Ted Kamenecka, New York, NY (US);

Erik J Sorensen, San Diego, CA (US);

Aaron Balog, New York, NY (US);

Kenneth A. Savin, New York, NY (US);

Scott Kuduk, Harleysville, PA (US);

Christina Harris, New York, NY (US);

Xiu-Guo Zhang, New York, NY (US);

Joseph R. Bertino, Branford, CT (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D277/22 ; C07D303/02 ; C07D313/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilones.


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